Our Services

We offer a comprehensive suite of services designed to de-risk high stakes clinical decisions.

Experts in health research methodology with extensive training in biostatistics, epidemiology and clinical operations, our team can help you answer a broad range of research questions, including:

  • Illustration of a medicine bottle, chart, and magnifying glass representing clinical study planning and research analysis.

    Study Planning

    Maximize impact and determine the optimal design for your clinical trials and RWE studies

  • Cloud-based data simulation and modelling icon with connected databases and computers representing strategic healthcare analytics.

    Simulation & Modelling

    Transparent, custom simulation & modelling frameworks to inform go/no-go decisions and guide strategic decision-making.

  • Human head with connected nodes and gears representing causal inference and advanced healthcare data analysis.

    Causal Inference

    Examine the drivers of observed outcomes from non-randomized data.

  • Connected network diagram representing indirect treatment comparisons and evidence-based clinical analysis.

    Indirect Treatment Comparisons

    Robust ITC methods to generate credible, decision-ready evidence.

  • Funnel and gear illustration representing evidence synthesis and systematic review methodologies.

    Evidence Synthesis

    Understand the totality of evidence on a given topic.

  • Healthcare document with medical symbol and dollar sign representing health economics and cost-effectiveness analysis.

    Health Economics

    Assess the cost-effectiveness and budget impact of therapies.

  • Connected server and data network illustration representing healthcare data science and advanced analytics.

    Data Science

    Garner unique insights with advanced visualizations

Our Core Services

Core Clinical Sciences arrow icon dark blue

At CCS, we tailor our solutions to meet the unique needs and goals of each project and client. Below are some of the services we offer. If you don’t see what you’re looking for, feel free to reach out—there’s a good chance we can help.

  • The design stage is critical to ensure clinical trial efficiency and to maximize the trial’s success. We use clinical trial simulations to go beyond conventional sample size and power calculations. Our specialties include Adaptive Trial Designsand Master Protocols to cultivate maximally efficient designs.

    • Adaptive Trial Designs

    • Basket and Umbrella Trials

    • Cluster Trials

    • Platform Trials

    • Biomarker-Guided Designs

    • Bayesian Designs

  • Statistical simulations using advanced models are valuable decision-making tools. They allow us to test different strategies and scenarios to determine the optimal way forward.

    • Microsimulation

    • Bayesian Network Modelling

    • Survival Analysis in the Presence of Intercurrent Events

    • Cost-Effectiveness Modelling

    • Model Calibration & Validation

  • With the increasing availability of Real-World Data (RWD), there's a need for new ways to analyze this nuanced information. We are always adding new 'Real-World Solutions' to our toolbox in order to provide the most effective services.

    • Real-World Data Landscape Analysis

    • External Control Arms (ECA)

    • Target Trial Emulation

    • Causal Inference: Propensity Score and Non-Propensity Score Adjustment Methods

    • Quantitative Bias Analysis (QBA)

    • Transportability Analysis

  • We work meticulously to identify all relevant evidence in the peer-reviewed and grey literature. We then synthesize that evidence using rigorous quantitative methods to give you the answers you need.

    • Literature Reviews and Epidemiological Studies

    • Meta-Analyses

    • Bayesian Network Meta-Analyses & Network Meta-Interpolation

    • Indirect Treatment Comparison (ITC)

    • Matched Adjusted Indirect Comparison (MAIC)

  • We build computational models to assess health economic impacts and support informed decision-making. Our services are designed to engage stakeholders effectively with data-driven insights for explicit decision-making.

    • Budget Impact Analysis

    • Cost-Effectiveness Analysis

    • Markov Models

    • Multi-Criteria Decision Analysis