Core Clinical Sciences

Agile. Adaptable. Solution-Oriented.

Our Mission

Deliver personalized consulting services that fit your needs and maximize your potential.

Our Services

  • We work meticulously to identify all relevant evidence in the peer-reviewed and grey literature. We then synthesize that evidence using rigorous quantitative methods to give you the answers you need.

    • Literature Reviews and Epidemiological Studies

    • Meta-Analyses

    • Bayesian Network Meta-Analyses & Network Meta-Interpolation

    • Indirect Treatment Comparison (ITC)

    • Matched Adjusted Indirect Comparison (MAIC)

  • With the increasing availability of Real-World Data (RWD), there's a need for new ways to analyze this nuanced information. We are always adding new 'Real-World Solutions' to our toolbox in order to provide the most effective services.

    • Real-World Data Landscape Analysis

    • External Control Arms (ECA)

    • Target Trial Emulation

    • Causal Inference: Propensity Score and Non-Propensity Score Adjustment Methods

    • Quantitative Bias Analysis (QBA)

    • Transportability Analysis

  • We build computational models to assess health economic impacts and support informed decision-making. Our services are designed to engage stakeholders effectively with data-driven insights for explicit decision-making.

    • Budget Impact Analysis

    • Cost-Effectiveness Analysis

    • Markov Models

    • Discrete Choice Experiments

    • Multi-Criteria Decision Analysis

    • Multi-Criteria Augmented Decision Analysis (MCADA)

  • Our company specializes in engagement with patients and stakeholders to demonstrate real-life impacts. We use both standardized and carefully crafted surveys and questionnaires to measure what matters most.

    • Clinical Trial Diversity Plans

    • Patient Reported Outcome Measurement

    • Surveys and Questionnaires

    • Qualitative and Mixed-Methods

    • Stakeholder Engagement

  • The design stage is critical to ensure clinical trial efficiency and to maximize the trial’s success. We use clinical trial simulations to go beyond conventional sample size and power calculations. Our specialties include Adaptive Trial Designs and Master Protocols to cultivate maximally efficient designs.

    • Adaptive Trial Designs

    • Basket and Umbrella Trials

    • Platform Trials

    • Biomarker-Guided Designs

    • Bayesian Designs

  • Our technical writing services complement our core services. We have a proven track record of publishing peer-reviewed publications in top-tier medical and statistical journals such as JAMA, the Lancet, Statistics in Medicine, and more. We also have experience preparing HTA, regulatory, public health, and global health guidance documents.

  • We have strong roots in academia and are passionate about teaching. With a wealth of experience in education and training, we can develop and deliver a customized workshop for your organization.

A team you can rely on.

Dedicated professionals, we have decades of combined experience providing bespoke health research solutions.